Whether it is physical or mental, vitamins B plays a very important role in managing stress. The body uses B vitamins during times of stress, an adequate amount is needed. These nutrients are also important for nerve and immune health. A toxic by-product of amino acid metabolism, high homocysteine levels have been associated with negative cardiovascular health. Folic acid, vitamin B6 and vitamin B12 are all essential for healthy support of homocysteine levels.